Causes of high or low creatinine in patients with kidney disease

In patients with nephropathy, the fluctuation of creatinine can be found in the clinical examination, and the blood creatinine is higher than normal, while the urine creatinine is lower than normal.
This is because the kidney after the invasion by various causes, first the damaged renal intrinsic cells phenotype transformation, the formation of pathological changes, stimulate renal fibroblasts into muscle in fibroblasts, and infringement and inspired the inherent normal kidney tissues, happen the same pathological changes, thus formed the kidney, from part to whole, enlarge the spread process, thus entered the organ damage period (i.e., kidney damage).
Causes of high or low creatinine in patients with kidney disease
At this time due to kidney damage, the function of the discharge of waste, resulting in the accumulation of the creatinine and other toxins in the body and blood creatinine and urea nitrogen increased, urine creatinine decreased, double kidney filtration rate drop, etc.
At the same time, the patient will also have high blood pressure, high swelling and other physical symptoms.

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