There are two main types of traditional hyperuric drugs
The first category: uricosuric drugs
1, probenecid
Probenecid is mainly used for the treatment of hyperuricemia with chronic gouty arthritis and tophi, provided that the body's glomerular filtration rate is greater than 50-60ml/min; there is no history of urinary stones or related history; urine Acidity and alkalinity requirements can not be acidic urine; can not use salicylic acid drugs.
2, benzbromarone
The benzbromarone is mainly used for the treatment of primary and secondary hyperuricemia, intermittent gouty arthritis and swollen gout tuberculosis, and the second type: inhibition of endogenous uric acid producing drugs
1, allyl alcohol
Allopurine drugs have been clinically used for more than 40 years and are mainly used for the treatment of hyperuricemia, gout, tophi, uric acid nephrolithiasis and uric acid nephropathy. The therapeutic effect is obvious and the cost is low.
The oral absorption rate of allopurine is more than 80%, but patients with abnormal liver and kidney function should pay attention to adjusting the dosage.
2, febuxostat
At present, it is mainly used for the long-term treatment of primary hyperuricemia, and there is an alternative treatment plan for treating allopurinol poorly or otherwise.
Absorption rate of allopurine is about 50%, and it is generally only when the liver and kidney function is significantly impaired.
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